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Article

Validation and comparison of pharmacogenetics-based warfarin dosing algorithms for application of pharmacogenetic testing.

The Journal of molecular diagnostics : JMD - 1 May 2010

Roper Nitin, Storer Barry, Bona Robert, Fang Min

Abstract excerpt

Warfarin is a widely prescribed drug that is difficult to use because of its narrow therapeutic window. Genetic polymorphisms associated with warfarin metabolism have been identified, but the clinical utility of genetic testing in warfarin dosing has not been established. External validation of published algorithms is critical to determine the best prediction for warfarin dosing in prospective trials. We used two...

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Identifiers

PMID: 20228265
DOI: 10.2353/jmoldx.2010.090110
PMCID: PMC2860463

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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