Article
Accuracy assessment of pharmacogenetic algorithms for warfarin dose prediction in Chinese patients.
American journal of hematology - 1 May 2012
Lei Xiaoying, Guo Yanhai, Sun Jianbin, Zhou Heping, Liu Yonglan, Liang Ping, Yan Zhen
Abstract excerpt
A few warfarin pharmacogenetic dosing algorithms have been proposed,based on multiethnic or homogeneous populations, to estimate warfarin therapeutic doses. However, it remains to be proven that which algorithm is accurate in predicting warfarin dose in Chinese people. We selected eight warfarin dose predictive pharmacogenetic algorithms and retrospectively assessed the predictive accuracy of each algorithm in a...
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