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Article

Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.

PloS one - 1 Jan 2011

Lingappa Jairam R, Petrovski Slavé, Kahle Erin, Fellay Jacques, Shianna Kevin, McElrath M Juliana, Thomas Katherine K, Baeten Jared M, Celum Connie, Wald Anna, de Bruyn Guy, Mullins James I, Nakku-Joloba Edith, Farquhar Carey, Essex Max, Donnell Deborah, Kiarie James, Haynes Bart, Goldstein David

Abstract excerpt

BACKGROUND: Host genetic factors may be important determinants of HIV-1 sexual acquisition. We performed a genome-wide association study (GWAS) for host genetic variants modifying HIV-1 acquisition and viral control in the context of a cohort of African HIV-1 serodiscordant heterosexual couples. To minimize misclassification of HIV-1 risk, we quantified HIV-1 exposure, using data including plasma HIV-1...

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Identifiers

PMID: 22174851
DOI: 10.1371/journal.pone.0028632
PMCID: PMC3236203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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