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Article

Testing for risk and protective trends in genetic analyses of HIV acquisition.

Biostatistics (Oxford, England) - 1 Apr 2015

Mccarthy Janice M, Shea Patrick R, Goldstein David B, Allen Andrew S

Abstract excerpt

Host genetics studies of HIV-1 acquisition are critically important for the identification of new targets for drug and vaccine development. Analyses of such studies typically focus on pairwise comparisons of three different groups: HIV-1 positive individuals, HIV-1 high-risk seronegative individuals, and population controls. Because there is a clear expectation of how gene frequencies of risk or protective...

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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25270736
DOI: 10.1093/biostatistics/kxu044
PMCID: PMC4441099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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