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Article

Mixture model for sub-phenotyping in GWAS.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2012

Warde-Farley David, Brudno Michael, Morris Quaid, Goldenberg Anna

Abstract excerpt

Genome Wide Association (GWA) studies resulted in discovery of genetic variants underlying several complex diseases including Chron's disease and age-related macular degeneration (AMD). Still geneticists find that in majority of studies the size of the effect even if it is significant tends to be very small. There are several factors contributing to this problem such as rare variants, complex relationships among...

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PMID: 22174291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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