Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sox10-iCreERT2 : a mouse line to inducibly trace the neural crest and oligodendrocyte lineage.

Genesis (New York, N.Y. : 2000) - 1 Jun 2012

Simon Christiane, Lickert Heiko, Götz Magdalena, Dimou Leda

Abstract excerpt

SOX10 is a well-conserved and widely expressed transcription factor involved in the regulation of embryonic development and in the determination of cell fate. As it is expressed in neural crest cells, their derivatives and the oligodendrocyte lineage, mutations of the protein contribute to a variety of diseases like neurocristopathies, peripheral demyelinating neuropathies, and melanoma. Here, we report the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Cell Differentiation
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrases

Share to Mice, Transgenic

Share to Neural Crest

Share to Oligodendroglia

Share to SOXE Transcription Factors

Source

Identifiers

PMID: 22173870
DOI: 10.1002/dvg.22003

Genes

SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sox10-iCreERT2 : a mouse line to inducibly trace the neural crest and oligodendrocyte lineage.PMID 22173870Read ↗

Oligodendroglial and pan‐neural crest expression of Cre recombinase directed by <i>Sox10</i> enhancerSemantic proximity Read ↗

Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10.Semantic proximity Read ↗

Sox10- Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytesSemantic proximity Read ↗

Sorting out Sox10 functions in neural crest development.Semantic proximity Read ↗

Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages.Semantic proximity Read ↗

Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.Semantic proximity Read ↗

Oligodendroglia generate vascular mural cells and neurons in the adult mouse brainSemantic proximity Read ↗

Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia.Semantic proximity Read ↗

The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord.Semantic proximity Read ↗

Gain of Olig2 function in oligodendrocyte progenitors promotes remyelinationSemantic proximity Read ↗

<i>Sox10</i> is required for Schwann‐cell homeostasis and myelin maintenance in the adult peripheral nerveSemantic proximity Read ↗

The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.