Article
Sox10- Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes
31 Oct 2010
Abstract excerpt
BACKGROUND: While several mouse strains have recently been developed for tracing neural crest or oligodendrocyte lineages, each strain has inherent limitations. The connection between human SOX10 mutations and neural crest cell pathogenesis led us to focus on the Sox10 gene, which is critical for neural crest development. We generated Sox10-Venus BAC transgenic mice to monitor Sox10 expression in both normal...
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