Article
Association between urothelial carcinoma after kidney transplantation and aristolochic acid exposure: the potential role of aristolochic acid in HRas and TP53 gene mutations.
Transplantation proceedings - 1 Dec 2011
Xiao J, Zhu X, Hao G Y, Zhu Y C, Hou H J, Zhang J, Ma L L, Tian Y, Zhang Y H
Abstract excerpt
OBJECTIVE: We sought to investigate the association between urothelial carcinoma (UC) after kidney transplantation and aristolochic acid (AA) exposure, and to explore the potential role of AA in HRas and TP53 gene mutations. MATERIALS AND METHODS: UC was confirmed in 100 of 3790 patients who underwent kidney transplantation between January 1974 and May 2011. We retrospectively analyzed clinical data for these...
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