Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.

International journal of cancer - 1 Jul 2013

Chen Chung-Hsin, Dickman Kathleen G, Huang Chao-Yuan, Moriya Masaaki, Shun Chia-Tung, Tai Huai-Ching, Huang Kuo-How, Wang Shuo-Meng, Lee Yuan-Ju, Grollman Arthur P, Pu Yeong-Shiau

Abstract excerpt

Aristolochic acid (AA), a component of all Aristolochia-based herbal medicines, is a potent nephrotoxin and human carcinogen associated with upper urinary tract urothelial carcinoma (UUC). To investigate the clinical and pathological characteristics of AA-induced UUC, this study included 152 UUC patients, 93 of whom had been exposed to AA based on the presence of aristolactam-DNA adducts in the renal cortex. Gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Transitional Cell
Share to Deoxyadenosines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Adducts

Share to Drugs, Chinese Herbal

Share to Heterocyclic Compounds, 4 or More Rings

Share to Neoplasms, Multiple Primary

Share to Neoplasms, Second Primary

Share to Urologic Neoplasms

Source

Identifiers

PMID: 23292929
DOI: 10.1002/ijc.28013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.PMID 23292929Read ↗

Aristolochic acid-associated urothelial cancer in TaiwanSemantic proximity Read ↗

Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease.Semantic proximity Read ↗

Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia.Semantic proximity Read ↗

Additive Effects of Arsenic and Aristolochic Acid in Chemical Carcinogenesis of Upper Urinary Tract UrotheliumSemantic proximity Read ↗

Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure.Semantic proximity Read ↗

Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivoSemantic proximity Read ↗

Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma.Semantic proximity Read ↗

DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial CancerSemantic proximity Read ↗

Mutation signatures implicate aristolochic acid in bladder cancer developmentSemantic proximity Read ↗

[Epidemiology and risk factors of upper urinary tract tumors: literature review for the yearly scientific report of the French National Association of Urology].Semantic proximity Read ↗

Aristolochic Acid in the Etiology of Renal Cell Carcinoma.Semantic proximity Read ↗

Mutational signatures in upper tract urothelial carcinoma define etiologically distinct subtypes with prognostic relevanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.