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Article

A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes.

BMC bioinformatics - 15 Dec 2011

Doherty Kathleen M, Nakka Priyanka, King Bracken M, Rhee Soo-Yon, Holmes Susan P, Shafer Robert W, Radhakrishnan Mala L

Abstract excerpt

BACKGROUND: Great strides have been made in the effective treatment of HIV-1 with the development of second-generation protease inhibitors (PIs) that are effective against historically multi-PI-resistant HIV-1 variants. Nevertheless, mutation patterns that confer decreasing susceptibility to available PIs continue to arise within the population. Understanding the phenotypic and genotypic patterns responsible for...

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Source

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Identifiers

PMID: 22172090
DOI: 10.1186/1471-2105-12-477
PMCID: PMC3305535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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