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Article

Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype.

Proceedings of the National Academy of Sciences of the United States of America - 11 Jun 2002

Beerenwinkel Niko, Schmidt Barbara, Walter Hauke, Kaiser Rolf, Lengauer Thomas, Hoffmann Daniel, Korn Klaus, Selbig Joachim

Abstract excerpt

Drug resistance testing has been shown to be beneficial for clinical management of HIV type 1 infected patients. Whereas phenotypic assays directly measure drug resistance, the commonly used genotypic assays provide only indirect evidence of drug resistance, the major challenge being the interpretation of the sequence information. We analyzed the significance of sequence variations in the protease and reverse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12060770
DOI: 10.1073/pnas.112177799
PMCID: PMC123057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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