Article
Characterizing the relationship between HIV-1 genotype and phenotype: prediction-based classification.
Biometrics - 1 Mar 2002
Foulkes A S, De Gruttola V
Abstract excerpt
This paper establishes a framework for understanding the complex relationships between HIV-1 genotypic markers of resistance to antiretroviral drugs and clinical measures of disease progression. A new classification scheme based on the probabilities of how new patients will respond to antiretroviral therapy given the available data is proposed as a method for distinguishing among groups of viral sequences. This...
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