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Article

A single mutation in 16S rRNA that affects mRNA binding and translation-termination.

Nucleic acids research - 25 Sept 1990

Prescott C D, Göringer H U

Abstract excerpt

A single base change in 16S rRNA (C726 to G) has previously been shown to have a dramatic effect on protein synthesis in E. coli (1). This paper more specifically details the effects of the mutation on mRNA binding and translation-termination. The in vitro technique of toeprinting (2) was used to demonstrate that 30S subunits containing the mutation 726G had an altered binding affinity for mRNA by comparison to...

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Identifiers

PMID: 2216710
DOI: 10.1093/nar/18.18.5381
PMCID: PMC332213

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