Article
A single mutation in 16S rRNA that affects mRNA binding and translation-termination.
Nucleic acids research - 25 Sept 1990
Prescott C D, Göringer H U
Abstract excerpt
A single base change in 16S rRNA (C726 to G) has previously been shown to have a dramatic effect on protein synthesis in E. coli (1). This paper more specifically details the effects of the mutation on mRNA binding and translation-termination. The in vitro technique of toeprinting (2) was used to...
Topics
- Base Sequence
- Codon
- Densitometry
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Peptide Termination Factors
- Protein Biosynthesis
- RNA, Messenger
- RNA, Ribosomal, 16S
- Ribosomes
- Transformation, Genetic