Article
Optimization of ribosome structure and function by rRNA base modification.
PloS one - 24 Jan 2007
Baxter-Roshek Jennifer L, Petrov Alexey N, Dinman Jonathan D
Abstract excerpt
BACKGROUND: Translating mRNA sequences into functional proteins is a fundamental process necessary for the viability of organisms throughout all kingdoms of life. The ribosome carries out this process with a delicate balance between speed and accuracy. This work investigates how ribosome structure and function are affected by rRNA base modification. The prevailing view is that rRNA base modifications serve to...
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