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Article

Ribosomal RNAs in translation termination: facts and hypotheses.

Biochemistry. Biokhimiia - 1 Dec 1999

Arkov A L, Murgola E J

Abstract excerpt

It is now well established that ribosomal RNAs (rRNAs) play an active role in every aspect of translation. This review focuses on recent evidence for the involvement of rRNAs from both subunits of the ribosome in translation termination. This evidence comprises data obtained with rRNA mutants both in vivo and in vitro. In particular, mutations in specific regions of rRNAs caused readthrough of nonsense codons in...

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PMID: 10648958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Ribosomal RNAs in translation termination: facts and hypotheses.PMID 10648958Read ↗

Mutations in conserved regions of ribosomal RNAs decrease the productive association of peptide-chain release factors with the ribosome during translation termination.Semantic proximity Read ↗

Ribosomal protein L11 mutations in two functional domains equally affect release factors 1 and 2 activity.Semantic proximity Read ↗

Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination.Semantic proximity Read ↗

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.Semantic proximity Read ↗

Global analysis of translation termination in E. coli.Semantic proximity Read ↗

Mutations at the accommodation gate of the ribosome impair RF2-dependent translation termination.Semantic proximity Read ↗

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Ribosomes containing the C1054-deletion mutation in E. coli 16S rRNA act as suppressors at all three nonsense codons.Semantic proximity Read ↗

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Variety of nonsense suppressor phenotypes associated with mutational changes at conserved sites in Escherichia coli ribosomal RNA.Semantic proximity Read ↗

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