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Article

Ribosomes containing the C1054-deletion mutation in E. coli 16S rRNA act as suppressors at all three nonsense codons.

Nucleic acids research - 11 Oct 1991

Prescott C, Krabben L, Nierhaus K

Abstract excerpt

It was established some time ago that the deletion of base C1054 in E. coli 16S rRNA specifically affects UGA-dependent termination of translation. Based on this observation, a model for the termination event was proposed in which the UGA nonsense codon on the mRNA base-pairs with a complementary motif in 'helix 34' of the 16S rRNA, thus potentially providing a recognition signal for the binding of the release...

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Identifiers

PMID: 1923812
DOI: 10.1093/nar/19.19.5281
PMCID: PMC328888

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Ribosomes containing the C1054-deletion mutation in E. coli 16S rRNA act as suppressors at all three nonsense codons.PMID 1923812Read ↗

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A rRNA-mRNA base pairing model for UGA-dependent termination.Semantic proximity Read ↗

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