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Article

Exon Arrays Reveal Alternative Splicing Aberrations in Parkinson’s Disease Leukocytes

9 Dec 2011

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is the second most frequent neurodegenerative disease worldwide. Clinical diagnosis can only be made when the vast majority of the dopaminergic cell population has died. However, the cause(s) for sporadic PD is/are yet unclear. Transcript changes have recently been described in PD patients' whole blood cells, but corresponding splicing patterns remained unknown. OBJECTIVE: To...

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PMID: 22156489
DOI: 10.1159/000332598

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