Article

A Comprehensive Study of Circulating Blood Linear RNA nominates CD55 and DLD as novel causal genes and early-stage biomarkers for Parkinson’s Disease

2025-06-20

Abstract excerpt

<h4>ABSTRACT</h4> We leveraged transcriptomic data from 4,343 participants from four independent datasets to robustly identify and annotate circulating PD-associated transcripts. We identified 296 differentially expressed transcripts, 28 of which were transcribed from known PD-associated loci. Further, we found a significant overlap between our findings and transcripts dysregulated in brain, as well as proteins d...

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Literature Corpus work: 11895ac6-82bf-58cf-b227-a84ecd37ee51
DOI: 10.1101/2025.06.20.25329948

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