Article

Prioritizing Parkinson’s Disease genes using population-scale transcriptomic data

2017-12-08

Abstract excerpt

Genome-wide association studies (GWAS) have identified over 41 susceptibility loci associated with late-onset Parkinson’s Disease (PD) but identifying putative causal genes and the underlying mechanisms remains challenging. To address this, we leveraged large-scale transcriptomic datasets to prioritize genes that are likely to affect PD. We found 29 gene associations in peripheral monocytes, and 44 gene associa...

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Literature Corpus work: 0ce9530d-5238-527a-835d-a5c526fafba4
DOI: 10.1101/231001

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