Article

A Blood Transcriptomic Resource for ALS Highlights Disease-Associated Signatures and Alternative Splicing Events

2025-07-28

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurogenerative disease resulting from progressive degeneration of motor neurons leading to systemic consequences. Despite being the most common motor neuron disease, with increasing global prevalence, limited treatment options exist. Emerging evidence from genetic studies and pathology analyses implicates RNA dysregulation in ALS pathogenesis, however, deep, comprehensive...

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Literature Corpus work: 684bb961-9d1d-5e82-8cdb-ec99594cf911
DOI: 10.1101/2025.07.28.25332310

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