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Article

The Exon-Based Transcriptomic Analysis of Parkinson’s Disease

19 Mar 2025

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disease with a complicated pathophysiology and diagnostics. Blood-based whole transcriptome analysis of the longitudinal PPMI cohort was performed with a focus on the change in the expression of exons to find potential RNA-based biomarkers. At the moment of diagnosis, the expression of exons was very similar in both control and PD patients. The exon-based analysis...

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PMID: 40149977
DOI: 10.3390/biom15030440

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