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Article

Presence of CXCR4-using HIV-1 in patients with recently diagnosed infection: correlates and evidence for transmission.

The Journal of infectious diseases - 15 Jan 2012

Chalmet Kristen, Dauwe Kenny, Foquet Lander, Baatz Franky, Seguin-Devaux Carole, Van Der Gucht Bea, Vogelaers Dirk, Vandekerckhove Linos, Plum Jean, Verhofstede Chris

Abstract excerpt

BACKGROUND: The prevalence and correlates of CXCR4-use in recently diagnosed patients and the impact of X4/DM transmission remain largely unknown. METHOD: Genotypic coreceptor use determination on the baseline sample of 539 recently diagnosed individuals. Correlation of coreceptor use with clinical, viral and epidemiological data and with information on transmission events as obtained through phylogenetic...

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Topics

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Share to CD4 Lymphocyte Count
Share to HIV Envelope Protein gp120

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Fragments

Share to Receptors, CCR5

Share to Receptors, CXCR4

Share to Sequence Analysis, RNA

Share to Statistics, Nonparametric

Share to Viral Tropism

Source

Identifiers

PMID: 22147802
DOI: 10.1093/infdis/jir714

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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