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Article

The temporal increase in HIV-1 non-R5 tropism frequency among newly diagnosed patients from northern Poland is associated with clustered transmissions.

Journal of the International AIDS Society - 1 Jan 2015

Parczewski Miłosz, Leszczyszyn-Pynka Magdalena, Witak-Jędra Magdalena, Maciejewska Katarzyna, Myślińska Sławomira, Urbańska Anna

Abstract excerpt

INTRODUCTION: CCR5 (R5) tropic viruses are associated with early stages of infection, whereas CXCR4 (X4) HIV-1 tropism has been associated with severe immunodeficiency. We investigated the temporal changes in the genotype-predicted tropism frequency and the phylogenetic relationships between the R5 and non-R5 clades. METHODS: A cohort of 194 patients with a newly diagnosed HIV infection that was linked to their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26297538
DOI: 10.7448/IAS.18.1.19993
PMCID: PMC4545195

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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