Article
Coreceptor usage of Chinese HIV-1 and impact of X4/DM transmission clusters among recently infected men who have sex with men.
Medicine - 1 Sept 2016
Li Xiaoshan, Zhu Kexin, Li Wei, Fang Kun, Musa Taha Hussein, Song Yue, Du Guoping, Gao Rong, Guo Yan, Yan Wenjuan, Xuan Yang, Zhong Ping, Wei Pingmin
Abstract excerpt
To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was performed on samples from 399 MSM individuals and on 2408 available Chinese HIV-1 V3 sequences...
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