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Article

Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals.

The Journal of infectious diseases - 1 Aug 2005

Brumme Zabrina L, Goodrich James, Mayer Howard B, Brumme Chanson J, Henrick Bethany M, Wynhoven Brian, Asselin Jerome J, Cheung Peter K, Hogg Robert S, Montaner Julio S G, Harrigan P Richard

Abstract excerpt

OBJECTIVE: We wished to characterize the epidemiological and clinical correlates of CXCR4-using human immunodeficiency virus type 1 (HIV-1) ("X4 variants") in a cross-sectional analysis of a large population of antiretroviral-naive individuals. METHODS: HIV-1 coreceptor use was determined in the last pretherapy plasma sample for 1191 individuals initiating triple-combination therapy in British Columbia, Canada....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15995960
DOI: 10.1086/431519

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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