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Article

Faster HIV-1 Disease Progression among Brazilian Individuals Recently Infected with CXCR4-Utilizing Strains

26 Jan 2012

Abstract excerpt

INTRODUCTION: Primary HIV infection is usually caused by R5 viruses, and there is an association between the emergence of CCXR4-utilizing strains and faster disease progression. We characterized HIV-1 from a cohort of recently infected individuals in Brazil, predicted the virus's co-receptor use based on the env genotype and attempted to correlate virus profiles with disease progression. METHODS: A total of 72...

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PMID: 22291931
DOI: 10.1371/journal.pone.0030292

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