Article
CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression.
AIDS (London, England) - 24 Sept 2010
Raymond Stéphanie, Delobel Pierre, Mavigner Maud, Cazabat Michelle, Encinas Stéphanie, Souyris Corinne, Bruel Patrick, Sandres-Sauné Karine, Marchou Bruno, Massip Patrice, Izopet Jacques
Abstract excerpt
OBJECTIVE: Cysteine-cysteine receptor 5 (CCR5)-using viruses classically predominate during HIV-1 primary infection but the frequency of cysteine-X-cysteine receptor 4 (CXCR4)-using viruses varies between studies and could be different between plasma and peripheral blood mononuclear cells (PBMCs). Thus, we determined HIV-1 tropism in both these compartments during primary infection and evaluated the impact of...
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