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Article

Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.

PLoS genetics - 1 Dec 2011

Fan Qiao, Zhou Xin, Khor Chiea-Chuen, Cheng Ching-Yu, Goh Liang-Kee, Sim Xueling, Tay Wan-Ting, Li Yi-Ju, Ong Rick Twee-Hee, Suo Chen, Cornes Belinda, Ikram Mohammad Kamran, Chia Kee-Seng, Seielstad Mark, Liu Jianjun, Vithana Eranga, Young Terri L, Tai E-Shyong, Wong Tien-Yin, Aung Tin, Teo Yik-Ying, Saw Seang-Mei

Abstract excerpt

Corneal astigmatism refers to refractive abnormalities and irregularities in the curvature of the cornea, and this interferes with light being accurately focused at a single point in the eye. This ametropic condition is highly prevalent, influences visual acuity, and is a highly heritable trait. There is currently a paucity of research in the genetic etiology of corneal astigmatism. Here we report the results...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22144915
DOI: 10.1371/journal.pgen.1002402
PMCID: PMC3228826

Genes

PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.PMID 22144915Read ↗

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