Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CMPK1 and RBP3 are associated with corneal curvature in Asian populations.

Human molecular genetics - 15 Nov 2014

Chen Peng, Miyake Masahiro, Fan Qiao, Liao Jiemin, Yamashiro Kenji, Ikram Mohammad K, Chew Merywn, Vithana Eranga N, Khor Chiea-Chuen, Aung Tin, Tai E-Shyong, Wong Tien-Yin, Teo Yik-Ying, Yoshimura Nagahisa, Saw Seang-Mei, Cheng Ching-Yu

Abstract excerpt

Corneal curvature (CC) measures the steepness of the cornea and is an important parameter for clinically diseases such as astigmatism and myopia. Despite the high heritability of CC, only two associated genes have been discovered to date. We performed a three-stage genome-wide association study meta-analysis in 12 660 Asian individuals. Our Stage 1 was done in multiethnic cohorts comprising 7440 individuals,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Cornea

Share to Eye Diseases

Share to Eye Proteins

Share to Retinol-Binding Proteins

Source

Identifiers

PMID: 24963161
DOI: 10.1093/hmg/ddu322

Genes

RBP3
CMPK1
MTOR
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CMPK1 and RBP3 are associated with corneal curvature in Asian populations.PMID 24963161Read ↗

Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.Semantic proximity Read ↗

A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α gene as a quantitative trait locus for eye size in white Europeans.Semantic proximity Read ↗

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error.Semantic proximity Read ↗

Corneal curvature-associated MTOR variant differentiates mild myopia from high myopia in Han Chinese population.Semantic proximity Read ↗

Heritability and Genetic Factors of Astigmatism and Corneal Curvature: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

Genetic variants near PDGFRA are associated with corneal curvature in Australians.Semantic proximity Read ↗

Association analysis of exome variants and refraction, axial length, and corneal curvature in a European-American population.Semantic proximity Read ↗

Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.Semantic proximity Read ↗

A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries.Semantic proximity Read ↗

A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness.Semantic proximity Read ↗

mTOR complex 1 pathway activation in severe keratoconus; the functional implications of GWAS identified lociSemantic proximity Read ↗

Genome-wide association study of quantitative ocular traits, including axial length and central corneal thickness, identifies loci for refractive error in the Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.