Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

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Article

Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

Molecular vision - 1 Jan 2013

Yazar Seyhan, Mishra Aniket, Ang Wei, Kearns Lisa S, Mountain Jenny A, Pennell Craig, Montgomery Grant W, Young Terri L, Hammond Christopher J, Macgregor Stuart, Mackey David A, Hewitt Alex W

Abstract excerpt

PURPOSE: Corneal astigmatism is a common eye disorder characterized by irregularities in corneal curvature. Recently, the rs7677751 single nucleotide polymorphism (SNP) at the platelet-derived growth factor receptor alpha (PDGFRA) locus was found to be associated with corneal astigmatism in people of Asian ancestry. In the present study, we sought to replicate this finding and identify other genetic markers of...

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Identifiers

PMID: 23761726
PMCID: PMC3675057

Genes

PDGFRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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