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Article

Genetic and functional analyses of the gene encoding synaptophysin in schizophrenia.

Schizophrenia research - 1 May 2012

Shen Yu-Chih, Tsai Ho-Min, Ruan Jhen-Wei, Liao Yi-Chu, Chen Shih-Fen, Chen Chia-Hsiang

Abstract excerpt

OBJECTIVES: Synaptophysin (SYP) has been shown to be critical for regulating neurotransmitter release and synaptic plasticity, a process thought to be disrupted in schizophrenia. In addition, abnormal SYP expression in different brain regions has been linked to this disorder in postmortem brain studies. We investigated the involvement of the SYP gene in the susceptibility to schizophrenia. METHODS: We searched...

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Identifiers

PMID: 22348818
DOI: 10.1016/j.schres.2012.01.028

Genes

SYP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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