Article
Gender-Specific Associations between CHGB Genetic Variants and Schizophrenia in a Korean Population.
Yonsei medical journal - 1 May 2017
Shin Joong Gon, Kim Jeong Hyun, Park Chul Soo, Kim Bong Jo, Kim Jae Won, Choi Ihn Geun, Hwang Jaeuk, Shin Hyoung Doo, Woo Sung Il
Abstract excerpt
PURPOSE: Schizophrenia is a devastating mental disorder and is known to be affected by genetic factors. The chromogranin B (CHGB), a member of the chromogranin gene family, has been proposed as a candidate gene associated with the risk of schizophrenia. The secretory pathway for peptide hormones and neuropeptides in the brain is regulated by chromogranin proteins. The aim of this study was to investigate the...
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