Article
Genetic analysis of GABRB3 at 15q12 as a candidate gene of schizophrenia.
Psychiatric genetics - 1 Aug 2014
Huang Chia-Chun, Cheng Min-Chih, Tsai Ho-Min, Lai Chih-Hao, Chen Chia-Hsiang
Abstract excerpt
OBJECTIVE: Copy number variations encompassing the chromosome 15q11-q13 region have been implicated in the pathogenesis of several neurodevelopmental disorders including schizophrenia. The study aimed to investigate whether the GABRB3 gene mapped to 15q12 was associated with schizophrenia. MATERIALS AND METHODS: We resequenced the promoter and all the exonic regions of the GABRB3 gene in 349 patients with...
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