Article
Genetic and functional analysis of the gene encoding neurogranin in schizophrenia.
Schizophrenia research - 1 May 2012
Shen Yu-Chih, Tsai Ho-Min, Cheng Min-Chih, Hsu Shih-Hsin, Chen Shih-Fen, Chen Chia-Hsiang
Abstract excerpt
OBJECTIVES: Schizophrenia is a highly heritable disorder, but many aspects of its etiology and pathophysiology remain poorly understood. Recently, a SNP rs12807809 located upstream of the neurogranin (NRGN) gene achieved genome-wide significance in this disorder. METHODS: In order to find the causal variants of NRGN gene in schizophrenia, we searched for genetic variants in the promoter region and all the exons...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
