Article
Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to environmental carcinogenesis?
Clinical genetics - 1 Sept 1998
Arruda V R, Grignolli C E, Gonçalves M S, Soares M C, Menezes R, Saad S T, Costa F F
Abstract excerpt
Environmental related diseases due to occupational carcinogens and toxic substances are a serious problem particularly in developing countries. The glutathione S-transferase system is fundamental for the detoxification of numerous carcinogens and mutagens. The individual inherited susceptibility...
Topics
- Alleles
- Brazil
- Carcinogens, Environmental
- Ethnicity
- Gene Deletion
- Gene Frequency
- Glutathione Transferase
- Homozygote