Article
Deletion of GSTM1 and T1 genes as a risk factor for development of acute leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Dunna Nageswara Rao, Vure Sugunakar, Sailaja K, Surekha D, Raghunadharao D, Rajappa Senthil, Vishnupriya S
Abstract excerpt
The glutathione S-transferases (GSTs) are a family of enzymes involved in the detoxification of a wide range of chemicals, including important environmental carcinogens, as well as chemotherapeutic agents. In the present study 294 acute leukemia cases, comprising 152 of acute lymphocytic leukemia (ALL) and 142 of acute myeloid leukemia, and 251 control samples were analyzed for GSTM1 and GSTT1 polymorphisms...
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