Article
Deletion polymorphism of glutathione S-transferases M1 and T1 in the Tunisian population.
La Tunisie medicale - 1 Oct 2010
Gara Sonia, Abessi Meriem, Bendjemena Katia, Abdennebi Monia, Guemira Fethi
Abstract excerpt
BACKGROUND: Glutathione S-transferases (GST) play a vital role in cellular defense against environmentally toxic compounds. These enzymes present a genetic deletion polymorphism, which varies with ethnicity. AIM: To evaluate the frequencies of homozygous deletion of GSTM1 and GSTT1 genes in Tunisian population. METHODS: On the basis of multiplex PCR protocol, the frequency of the deleted genotypes of GSTM1 and...
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