Article
Genetic polymorphism of the glutathione S-transferase M1 and T1 genes in three distinct Arab populations.
Disease markers - 1 Jan 2011
Salem Abdel Halim, Yaqoob Alaeddin, Ali Muhalab, Handu Shailandra, Fadel Raouf, Abu-Hijleh Marwan, Almawi Wassim
Abstract excerpt
Deletion polymorphisms for the glutathione S-transferase (GST) gene are associated with increased risk of cancer, and are implicated in detoxifying mutagenic electrophilic compounds. GST Polymorphic variants were reported for different populations. The aim of this study was to investigate the frequencies of GSTM1 and GSTT1 null genotypes among Bahraini, Lebanese and Tunisian Arabs. GST genotyping was done by...
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