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Article

Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.

Basic & clinical pharmacology & toxicology - 1 May 2012

Sortica Vinicius de A, Ojopi Elida B, Genro Júlia P, Callegari-Jacques Sidia, Ribeiro-Dos-Santos Andrea, de Moraes Manoel Odorico, Romano-Silva Marco A, Pena Sérgio D J, Suarez-Kurtz Guilherme, Hutz Mara H

Abstract excerpt

The frequency distribution of SNPs and haplotypes in the ABCB1, SLCO1B1 and SLCO1B3 genes varies largely among continental populations. This variation can lead to biases in pharmacogenetic studies conducted in admixed populations such as those from Brazil and other Latin American countries. The aim of this study was to evaluate the influence of self-reported colour, geographical origin and genomic ancestry on...

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Source

Identifiers

PMID: 22136368
DOI: 10.1111/j.1742-7843.2011.00838.x

Genes

ABCB1

Variants

rs4149056
rs2306283
rs11045819
rs4149117
rs1128503
rs2032582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.PMID 22136368Read ↗

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