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Article

Distribution of ABCB1 polymorphisms among Brazilians: impact of population admixture.

Pharmacogenomics - 1 Mar 2008

Estrela Rita C E, Ribeiro Fábio S, Carvalho Renato S, Gregório Sheila P, Dias-Neto Emmanuel, Struchiner Cláudio J, Suarez-Kurtz Guilherme

Abstract excerpt

INTRODUCTION: Interethnic admixture is a source of cryptic population structure that may lead to spurious genotype-phenotype associations in pharmacogenomic studies. We studied the impact of population stratification on the distribution of ABCB1 polymorphisms (1236C>T, 2677G>T/A and 3435C>T) among Brazilians, a highly admixed population with Amerindian, European and African ancestral roots. METHODS: Individual...

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PMID: 18303963
DOI: 10.2217/14622416.9.3.267

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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