Article
Genetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative.
The pharmacogenomics journal - 1 Dec 2018
Rodrigues-Soares Fernanda, Kehdy Fernanda S G, Sampaio-Coelho Julia, Andrade Poliana X C, Céspedes-Garro Carolina, Zolini Camila, Aquino Marla M, Barreto Mauricio L, Horta Bernardo L, Lima-Costa Maria Fernanda, Pereira Alexandre C, LLerena Adrián, Tarazona-Santos Eduardo
Abstract excerpt
We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil, and their distribution on self-reported race/color categories that: (1) involve a mix of perceptions about ancestry, morphological traits, and cultural/identity issues, being social constructs pervasively used in Brazilian society and medical studies; (2) are associated with disparities in access to health services, as well...
Topics
- Brazil
- Databases, Genetic
- Gene Frequency
- Haplotypes
- Health Status Disparities
- Healthcare Disparities
- Heredity
- Humans
- Pedigree