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Article

The epistasis between vascular homeostasis genes is apparent in essential hypertension.

Atherosclerosis - 1 Feb 2012

Kumar Rahul, Nejatizadeh Azim, Gupta Mohit, Markan Amandeep, Tyagi Sanjay, Jain S K, Pasha M A Qadar

Abstract excerpt

OBJECTIVE: The epistasis influence of vascular homeostasis genes is vital to multigenetic diseases. This study was designed to perceive the possible role of epistasis in the etiology of essential hypertension. METHODS: We investigated seven polymorphisms of ACE, CYP11B2 and NOS3 epistatically, and SBP, DBP, MAP, ACE activity, plasma aldosterone concentration (PAC) and NOx level in 860 age- and ethnicity-matched...

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Source

Identifiers

PMID: 22134143
DOI: 10.1016/j.atherosclerosis.2011.10.036

Genes

NOS3
ACE
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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