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Article

Multi-locus interactions of vascular homeostasis genes in essential hypertension: a gender-based study.

Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2009

Kumar Rahul, Nejatizadeh Azim, Arif Ehtesham, Akhtar Salman, Gupta Mohit, Tyagi Sanjay, Goyal A K, Jain S K, Qadar Pasha M A

Abstract excerpt

BACKGROUND: Studies on genes of endothelial and vascular homeostasis are inadequate in females. METHODS: We investigated the role of 7 variants of ACE, AGT and NOS3 and their correlation with NO(x) levels and ACE activity in hypertension susceptibility in 910 case-controls of both genders. RESULTS: Prevalence of alleles D of ACE I/D; -6A of AGT -6G/A; -786C, 894T and 4a of NOS3 -786T/C, 894G/T and 4b/4a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19379721
DOI: 10.1016/j.cca.2009.04.010

Genes

AGT
NOS3
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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