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Associations of CYP4A11 gene-gene and gene-smoking interactions with essential hypertension in the male eastern Chinese Han population.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2017

Zhang Huimin, Jin Limin, Mu Tonglu, Fan Yingying, Zhang Haiyang, Zhu Yuhua, Mao Xujie, Li Rong, Tang Siyuan

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the impact of CYP4A11 single-nucleotide polymorphisms (SNP), additional gene-gene and gene-environment interactions on essential hypertension (EH) risk. METHODS: A total of 1648 participants (788 males, 860 females), with a mean age of 56.1 ± 14.1 years old, were selected, including 820 EH patients and 828 normotension subjects. Logistic regression was...

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PMID: 28534704
DOI: 10.1080/10641963.2016.1267201

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DBP

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