Article
Functional SNP -1562C/T in the promoter region of MMP9 and recurrent early pregnancy loss.
Reproductive biomedicine online - 1 Jan 2012
Singh Kiran, Nair Rohini R, Khanna Anuradha
Abstract excerpt
Angiogenesis, invasion and decidualization play an important role in uterine preparation and embryo development. Matrix metalloproteinases (MMP) are crucial for the degradation/remodelling of the extracellular matrix and are involved in spiral artery formation and invasion of endometrium during implantation. A functional single-nucleotide polymorphism (SNP) in the MMP9 promoter, 1562C/T, is known to influence...
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