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Article

Matrix metalloproteinases 1, 2, 3 and 9 functional single-nucleotide polymorphisms in idiopathic recurrent spontaneous abortion.

Reproductive biomedicine online - 1 May 2012

Pereza Nina, Ostojić Saša, Volk Marija, Kapović Miljenko, Peterlin Borut

Abstract excerpt

Idiopathic recurrent spontaneous abortion (IRSA) has been associated with abnormalities in the remodelling of endometrial extracellular matrix, as well as aberrant matrix metalloproteinase (MMP) gene expression in endometrium of IRSA women and chorionic villi of IRSA concept. This study investigated the association of five functional MMP gene promoter polymorphisms (MMP1 -1607 1G/2G, MMP2 -735 C/T, MMP2 -1306...

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Source

Identifiers

PMID: 22406112
DOI: 10.1016/j.rbmo.2012.01.008

Genes

MMP2
MMP9
MMP1
MMP3

Provenance

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