Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of MMP2 and MMP9 gene polymorphisms with the recurrent spontaneous abortion: A meta-analysis.

Gene - 30 Jan 2021

Yan Yang, Fang Lanlan, Li Yuxi, Yu Yiping, Li Yiran, Cheng Jung-Chien, Sun Ying-Pu

Abstract excerpt

BACKGROUND: Recurrent spontaneous abortion (RSA) accounts for the most common complication of early pregnancy in humans. Matrix metalloproteinases (MMPs) play important regulatory roles in implantation and placentation to ensure a successful pregnancy. Single nucleotide polymorphisms (SNPs) have been identified in the promoters of MMP2 and MMP9 genes. However, the associations between MMP2 and MMP9 SNPs and the...

Topics

Join the communities discussing this publication.

Abortion, Spontaneous
Genome-Wide Association Study
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Matrix Metalloproteinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Source

Identifiers

PMID: 33007375
DOI: 10.1016/j.gene.2020.145173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of MMP2 and MMP9 gene polymorphisms with the recurrent spontaneous abortion: A meta-analysis.PMID 33007375Read ↗

Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population.Semantic proximity Read ↗

Evaluation of MMP-2 (-1306C/T and -735C/T), MMP-9 (-1562C/T) and TNF-alpha (-308G/A) promoter variants in recurrent spontaneous abortionSemantic proximity Read ↗

Systematic review and meta-analysis of genetic association studies in idiopathic recurrent spontaneous abortion.Semantic proximity Read ↗

MMP2 and MMP9 are associated with the pathogenesis of recurrent pregnancy loss through protein expression rather than genetic polymorphism.Semantic proximity Read ↗

Role of Polymorphisms on the Recurrent Pregnancy Loss: A Systematic Review, Meta-analysis and Bioinformatic Analysis.Semantic proximity Read ↗

Association of MMP-2, MMP-3, and MMP-9 Polymorphisms with Susceptibility to Recurrent Pregnancy Loss.Semantic proximity Read ↗

Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphisms in the fibrinolytic pathway genes and the risk of recurrent spontaneous abortion.Semantic proximity Read ↗

Matrix metalloproteinases 1, 2, 3 and 9 functional single-nucleotide polymorphisms in idiopathic recurrent spontaneous abortion.Semantic proximity Read ↗

Associations between various possible promoter polymorphisms of MMPs genes and endometriosis risk: a meta-analysis.Semantic proximity Read ↗

Logistic regression analysis of key markers of pre-thrombotic state screening in RSA patientsSemantic proximity Read ↗

Functional SNP -1562C/T in the promoter region of MMP9 and recurrent early pregnancy loss.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.