Article
Fetal MMP2/MMP9 polymorphisms and intrauterine growth restriction risk.
Journal of reproductive immunology - 1 Jun 2007
Gremlich Sandrine, Nguyen Daniel, Reymondin Danielle, Hohlfeld Patrick, Vial Yvan, Witkin Steven S, Gerber Stefan
Abstract excerpt
Poor embryo implantation can lead to poor feto-maternal exchanges and intrauterine growth restriction. Matrix metalloproteinase-2 (MMP-2) and MMP-9 are highly involved in early embryo implantation and three functional polymorphisms have been described for these genes: MMP2 C-1306T, MMP9 C-1562T and MMP9 (CA)n repeat. We evaluated therefore the association between fetal genotype for these mutations and...
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