Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MMP2 and MMP9 are associated with the pathogenesis of recurrent pregnancy loss through protein expression rather than genetic polymorphism.

Journal of reproductive immunology - 1 Aug 2024

Goto Shinobu, Ozaki Yasuhiko, Mori Ryosuke, Ozawa Fumiko, Obayashi Yuki, Kitaori Tamao, Sugiura-Ogasawara Mayumi

Abstract excerpt

Matrix metalloproteinases (MMPs) degrade extracellular matrix proteins and are important for placenta formation during early pregnancy. Recurrent pregnancy loss (RPL) is associated with abnormalities in endometrial extracellular matrix remodeling. This study aimed to elucidate the roles of MMP2 and MMP9 in RPL pathogenesis. In total, 295 women with a history of RPL and 101 controls were included in this genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Decidua

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Polymorphism, Single Nucleotide

Share to Pregnancy

Source

Identifiers

PMID: 38878627
DOI: 10.1016/j.jri.2024.104270

Genes

MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MMP2 and MMP9 are associated with the pathogenesis of recurrent pregnancy loss through protein expression rather than genetic polymorphism.PMID 38878627Read ↗

Association of MMP-2, MMP-3, and MMP-9 Polymorphisms with Susceptibility to Recurrent Pregnancy Loss.Semantic proximity Read ↗

Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population.Semantic proximity Read ↗

Association of MMP2 and MMP9 gene polymorphisms with the recurrent spontaneous abortion: A meta-analysis.Semantic proximity Read ↗

Functional SNP -1562C/T in the promoter region of MMP9 and recurrent early pregnancy loss.Semantic proximity Read ↗

Matrix metalloproteinases 1, 2, 3 and 9 functional single-nucleotide polymorphisms in idiopathic recurrent spontaneous abortion.Semantic proximity Read ↗

Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta-analysis.Semantic proximity Read ↗

Extracellular matrix metalloproteinases inducer gene polymorphism and reduced serum matrix metalloprotease-2 activity in preeclampsia patientsSemantic proximity Read ↗

Analysis of copy number variations and candidate genes in recurrent pregnancy loss.Semantic proximity Read ↗

Association of VEGF and p53 Polymorphisms and Spiral Artery Remodeling in Recurrent Pregnancy Loss: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Fetal MMP2/MMP9 polymorphisms and intrauterine growth restriction risk.Semantic proximity Read ↗

Collagenases MMP-1, MMP-13, and Tissue Inhibitors TIMP-1, TIMP-2: Their Role in Healthy and Complicated Pregnancy and Potential as Preeclampsia Biomarkers—A Brief ReviewSemantic proximity Read ↗

Expressional and epigenetic alterations of placental matrix metalloproteinase 9 in preeclampsiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.