Article
Matrix metalloproteinase (MMP)-9 genotypes and haplotypes in preeclampsia and gestational hypertension.
Clinica chimica acta; international journal of clinical chemistry - 3 Jun 2010
Palei Ana C T, Sandrim Valeria C, Duarte Geraldo, Cavalli Ricardo C, Gerlach Raquel F, Tanus-Santos Jose E
Abstract excerpt
BACKGROUND: Abnormal production of matrix metalloproteinases (MMPs), especially MMP-9, may play a role in hypertensive disorders of pregnancy. These alterations may result from functional genetic polymorphisms in the promoter region of MMP-9 gene, which are known to change MMP-9 expression. We examined whether 2 MMP-9 polymorphisms (C(-1562)T and (CA)n) and haplotypes are associated with preeclampsia and/or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
